Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
dissociation constant
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
other information
Study period:
2001
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001
Report date:
2001

Materials and methods

GLP compliance:
no

Results and discussion

Dissociating properties:
no

Applicant's summary and conclusion

Executive summary:

The chemical structure of ZK 92136 does not show any groups which can be protonated or deprotonated. This fact was supported by calculation with the computer programs ACD/pKa DB and CAMEO, which did not calculate for ZK 92136 any pKa value in the pH range 0 to 14. Therefore, ZK 92136 can be considered as a neutral molecule in the pH range 2 to 10, which is of relevance for biological systems.

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