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Description of key information

Oral (Rat, GLP, OECD TG 423): LD50 > 2000 mg/kg
[Schering AG, Report No. X240 -draft-, 1997-08-22]
Dermal (Rat, GLP, OECD TG 402): LD50 > 2000 mg/kg
[Schering AG, Report No. X302 -draft-, 1998-09-10]

Key value for chemical safety assessment

Additional information

The single oral administration of the test substance (ZK 92136) to male and female rats at a dose of 2000 mg/kg was tolerated without any mortality and compound-related clinical or macroscopic pathological signs. The acute oral toxicity of Dipivalat in rats is above 2000 mg/kg body weight.

The single dermal administration of the test substance (ZK 92136) to male and female rats at a dose of 2000 mg/kg was tolerated without any mortality and compound-related clinical or macroscopic pathological signs. The acute dermal toxicity of Dipivalat in rats is above 2000 mg/kg body weight.

Justification for classification or non-classification

Based on the study results a classification according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (CLP) is not required.

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