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According to the key biodegradation study (OECD Guideline 301 F, EU Method C.4 -D with GLP statement), the registered substance, METHYL CIS-3-OXO-2-PENTYL-1-CYCLOPENTANE ACETATE, attained 79% biodegradation after 28 days of incubation without strictly meeting the 10-day window criterion in one replicate (59% biodegradation at the end of the 10d window). Nonetheless and with regard to this very marginal failure (the mean of the two replicates met the 10 day window), the assessment can conclude that the substance is readily biodegradable. Furthermore, supporting evidence for this conclusion is available on two analogue materials showing readily biodegradability. These analogues are mixtures of two diastereomers, the first one is a quality high trans (ca. 10% cis- and 90% trans-diastereomers) and the other one is a quality high cis (ca. 71 to 76% cis- and 20 to 25% trans-diastereomers), which cis-diastereomer corresponds to the registered substance (monoconstituent).

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