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EC number: 938-458-7 | CAS number: 1443751-77-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In a study conducted according to OECD Guideline 202 and EU Method C.2 and using Daphnia magna as test organism, the EC50 value was 74.5 mg/L and the LOEC and NOEC values were 80.8 and 40.9 mg/L, respectively, after 48 h of exposure.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 74.5 mg/L
Additional information
One GLP Guideline study conducted according to OECD 202 is available investigating the short-term effects of Amides, C8-10, N-(hydroxyethyl) (CAS 1443751-77-6) to freshwater invertebrates (Evonik Industries, 2013).
Daphnids were exposed to control and test chemical at nominal concentration of 6.25, 12.5, 25.0, 50.0 and 100 mg/L.The geometric mean measured concentrations were 3.82, 8.54, 19.1, 40.9 and 80.8 mg/Lfor 48 hr. Immobilization was observed daily. The 48 – hour EC50was 74.5 mg/L. The 48 – hr NOEC based on immobilization was 40.9 mg/L (nominal 50.0 mg/L).
This study is classified as acceptable and satisfies the guideline requirements for an acute toxicity study with freshwater invertebrates.
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