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Ecotoxicological information

Toxicity to microorganisms

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Reference
Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data is from peer-reviewed journal
Justification for type of information:
Data is from peer-reviewed journal
Qualifier:
according to
Guideline:
other: as mentioned below
Principles of method if other than guideline:
A test was developed using Tetrahymena pyriformis in order to determine the toxicity of test material. The concentration of the chemical, at which the inhibition of test organism i.e T. pyriformis was observed (IC50), was determined.
GLP compliance:
not specified
Analytical monitoring:
no
Vehicle:
yes
Remarks:
<=0.75 % of Sulfinyl bis(methane)
Test organisms (species):
Tetrahymena pyriformis
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
Details on test conditions:
- No. of vessels per concentration (replicates): >=3 Replicates
Reference substance (positive control):
not specified
Duration:
48 h
Dose descriptor:
IC50
Effect conc.:
161.27 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
other: Population growth rate
Validity criteria fulfilled:
not specified
Conclusions:
The Inhibition concentration (IC50) of test material in tetrahymena pyriformis was observed to be 161.27 mg/L on the basis of population growth rate effect in a 48.0 hours of exposure.
Executive summary:

A test was developed using Tetrahymena pyriformis in order to determine the toxicity of test material. The concentration of the chemi cal, at which the inhibition of test organism i.e T. pyriformis was observed (IC50), was determined. The Inhibition concentration (IC50) of test material in tetrahymena pyriformis was observed to be 161.27 mg/L on the basis of population growth rate effect in a 48.0 hours of exposure.

Description of key information

Toxicity to microorganisms:

A test was developed using Tetrahymena pyriformis in order to determine the toxicity of test material. The concentration of the chemi cal, at which the inhibition of test organism i.e T. pyriformis was observed (IC50), was determined. The Inhibition concentration (IC50) of test material in tetrahymena pyriformis was observed to be 161.27 mg/L on the basis of population growth rate effect in a 48.0 hours of exposure.

Key value for chemical safety assessment

EC50 for microorganisms:
161.27 mg/L

Additional information

Toxicity to microorganisms:

A test was developed using Tetrahymena pyriformis in order to determine the toxicity of test material. The concentration of the chemi cal, at which the inhibition of test organism i.e T. pyriformis was observed (IC50), was determined. The Inhibition concentration (IC50) of test material in tetrahymena pyriformis was observed to be 161.27 mg/L on the basis of population growth rate effect in a 48.0 hours of exposure.