Registration Dossier
Registration Dossier
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EC number: 224-970-1 | CAS number: 4584-46-7
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- further information relevant for the PBT assessment is necessary
- Justification:
DMC is not classified as carcinogenic (cat 1A or 1B), cell mutagenic (category 1A or 1B) or toxic for reproduction (category 1A, 1B or 2) in accordance with EC No. 1272/2008. There is evidence of Specific Target Organ Toxicity (repeated exposure) category 2. This is an indication that DMC has the potential to be classed as toxic. However there is results available from OECD testing that shows the LC50 and EC50 concentrations are well in excess of the <0.1 mg/L criterion to be classed as toxic. Based on the actual OECD test result DMC is not T.
With respect to bioaccumulation the estimated Log Kow for DMC is < 4.5 and so is not B and not vB. In addition the bio accumulation factor for DMC is 3.16 L/Kg (experimentally determined or estimated by valid EPI suit) below the > 2000 L/kg threshold for BCF.
Therefore the overall conclusion is that DMC is not PBT.
- Likely routes of exposure:
The substance is not classified as PBT therefore there route of exposure is not relevant.
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