Registration Dossier
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EC number: 216-133-4 | CAS number: 1506-02-1
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Experiment conducted to specifically determine the melting temperature of AHTN. The experiment is conducted in-house at PFW (non-GLP).
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- capillary method
- Melting / freezing pt.:
- 55.1 °C
- Atm. press.:
- 1 atm
- Decomposition:
- no
- Sublimation:
- no
- Remarks on result:
- other: at 98.0% AHTN concentration in Tonalid
- Melting / freezing pt.:
- 54.5 °C
- Atm. press.:
- 1 atm
- Decomposition:
- no
- Sublimation:
- no
- Remarks on result:
- other: at 97.0% AHTN concentration in Tonalid
- Conclusions:
- The melting point of the substance is 54 °C.
- Executive summary:
A relationship between the melting point of Tonalid and the AHTN concentration in Tonalid was established. The AHTN concentration was determined with gas chromatography and the melting temperaturature with the capillary method.
Reference
A linear relationship exists between the melting point and the purity of the active substance concentration in Tonalid).
Description of key information
Melting point depends on the purity of the material and ranges from 54°C to 56°C 97.0-99.2%, tested according to the EU method A.1 guideline.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 54 °C
Additional information
Determination of the melting point is a standard quality control parameter. The test item concentration was determined with gas chromatography and the melting temperature with the capillary method. The melting point is linear related with the purity varying from 54 °C to 56 °C in the range of 97.0% to 99.2% of the test item.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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