Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable publication which meets basic scientific principles

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Evaluation of the genotoxic potential of some microbial volatile organic compounds (MVOC) with the comet assay, the micronucleus assay and the HPRT gene mutation assay
Author:
Kreja L and Seidel HJ
Year:
2002
Bibliographic source:
Mutation Research, 513(1-2), 143-150
Reference Type:
secondary source
Title:
No information
Author:
RIFM
Year:
2002
Bibliographic source:
RIFM database

Materials and methods

Type of study / information:
Cytotoxicity
Test guideline
Qualifier:
no guideline available
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-methylbutan-1-ol
EC Number:
205-289-9
EC Name:
2-methylbutan-1-ol
Cas Number:
137-32-6
Molecular formula:
C5H12O
IUPAC Name:
.
Details on test material:
- Name of test material (as cited in study report): 2-Methyl-1-butanol

Results and discussion

Any other information on results incl. tables

2 -Methyl-1 -butanol: IC50 = 31 mM

MMS: IC50 = 0.2 mM

Applicant's summary and conclusion