Registration Dossier
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EC number: 247-611-0 | CAS number: 26322-14-5
Endpoint summary
Administrative data
Description of key information
Several aquatic studies have been performed.
The acute toxicity of the test chemical to Daphnia Magna prepared as a Water Accommodated Fraction (WAF) was determined according to OECD 202 in a semi-static system over an exposure period of 48 hours at a loading concentration of 100 mg/L. The EL50 (48h) was > 100 mg/L (Loading).
The test substance was concluded as not acutely toxic to Daphnia at its solubility limit in the test media.
Attempt for an OECD 210 (FELS) test has been done on the read across source 53220 -22 -7, and results from the pretest is avaible. Due to the analytical struggles and the substances properties, the performance of the FELS study has been postponed in time and thus, the CCh deadline could not be met accordingly. As soon as any results from the CRO are available, the technical dossier will be accordingly updated.
Also chronic toxicity was determined in a flow-through system with 1 g (loading) according to OECD 211 over a period of 21 days. No effects on reproduction were observed and therefore NOELR (21d)≥ water solubility limit (1 g loading).
The test substance was concluded as not chronically toxic to Daphnia at its solubility limit in the test media.
The toxicity of the test chemical to an exponentially growing culture of P. subcapitata was determined as a Water Accommodated Fraction (WAF)
over an exposure period of 72 hours. A nominal loading concentration of 100 mg/L as a limit test was conducted.
No significant statistical difference in growth rate or biomass was detected in comparison to the control, therefore ErL50 (72h) > 100 mg/L (loading) and NOELR (72h)≥ 100 mg/L (loading).
The test substance was concluded as not toxic to algae at its solubility limit in the test medium.
Toxicity to microorganisms was determined as well in an activated sludge respiration inhibition test was performed according to OECD 209.
The EC50 (3h) of the substance for activated sludge is > 1220 mg/L. The substance is therefore considered harmless to activated sludge.
Considering the ready biodegradability, lack of detectable toxicity the test substance and low water solubility the substance is not expected to present a hazard to the aquatic environment.
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