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EC number: 293-346-9 | CAS number: 91078-64-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1971
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 971
- Report date:
- 1971
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- no guideline available
- GLP compliance:
- no
- Test type:
- acute toxic class method
- Limit test:
- no
Test material
- Reference substance name:
- Naphthalenesulfonic acids, branched and linear Bu derivs., sodium salts
- EC Number:
- 293-346-9
- EC Name:
- Naphthalenesulfonic acids, branched and linear Bu derivs., sodium salts
- Cas Number:
- 91078-64-7
- Molecular formula:
- Not applicable (UVCB substance)
- IUPAC Name:
- Reaction products of naphtalene, butanol, sulfonated and neautralized by caustic soda
- Test material form:
- solid: particulate/powder
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- water
- Doses:
- 500, 1000, 1500, 1750, 1850, 2000, 2550 mg/kg
- No. of animals per sex per dose:
- 15 males per dose group.
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 1 790 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: 14 days
Any other information on results incl. tables
Oral administration
Administration was performed by means of a gavage.
Male rats
A.I. dose mg/kg |
Toxicological Results after 14 days |
Signs of intoxication |
Died after no. days |
|
start |
end |
|||
500 |
0/15 |
- |
- |
- |
1000 |
0/15/15 |
2h |
2d |
- |
1500 |
0/15/15 |
2h |
2d |
- |
1750 |
4/15/15 |
2h |
3d |
1-3 |
1850 |
11/15/15 |
1.5h |
2d |
1 |
2000 |
12/15/15 |
Ih |
3d |
1-2 |
2250 |
15/15/15 |
Ih |
- |
1 |
Results: DL50 (14 days) 1790 mg A.I./kg (1700-1890)
S = 1.1
Highest dose without findings: 500 mg/kg
Lowest lethal dose: 1750 mg/kg
Applicant's summary and conclusion
- Interpretation of results:
- other: classified as harmful (Acute Tox.4) according to the CLP Regulation (EC) No.1272/2008
- Conclusions:
- The DL50 in male rats (14 days) 1790 mg A.I./ kg (1700-1890).
- Executive summary:
The toxicity of the substance after single exposure of rats was evaluated after the exposure of male Wistar rats to the substance at the concentrations 500, 1000, 1500, 1750, 1850, 2000, 2550 mg/kg bw.
The LD50 was found as 1790 mg/kg
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