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Physical & Chemical properties

Melting point / freezing point

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Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
5 October to 13 November 1998
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study data conducted to recent EU test guideline in compliance with GLP and reported with a GLP certificate

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1998
Report date:
1998

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
other: Differential Scanning Calorimetry.

Test material

Constituent 1
Details on test material:
- Physical state: POWDER
- Analytical purity: 94.7
- Lot/batch No.: HI295
- Expiration date of the lot/batch: 3 years in refrigerator and dry

Results and discussion

Melting / freezing point
Melting / freezing pt.:
157.4 °C
Decomposition:
yes
Remarks:
decomposition energy of 1243 J/g
Decomp. temp.:
>= 180 - <= 350 °C

Any other information on results incl. tables

The determination of the melting point by DSC, Mettler-Toledo TA8000, were carried out in closed glass pan and in closed aluminium pan. The measurement in the closed glass pan shows an endothermic effect (melting) in the range 130-170 °C and a decomposition of the test substance in the range 180-350 °C, with a decomposition energy of 1243 J/g. So the test for explosive properties has to be performed. In the aluminium pan the diagram shows a broad endothermal effect in the range 115-170 °C.

Mean melting point is 157.4 °C.

Ident. No.

onset temperature / °C

3606*

159.7

3607

156.8

3608

158.0

*glass

Applicant's summary and conclusion

Conclusions:
Mean melting point is 157.4 °C
Executive summary:

Study data conducted to Guideline 92/69/EEC of 31 July 1992, Annex. Part A: Methods for the determination of physico-chemical properties. A.1. melting point / melting range by differential scanning calorimetry (DSC) in accordance to GLP.

The mean melting point is 157.4 °C with decomposition of the test substance in the range 180-350 °C, with a decomposition energy of 1243 J/g.