Registration Dossier
Registration Dossier
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EC number: 206-735-5 | CAS number: 371-40-4
Biodegradation in water and sediment: simulation tests
Administrative data
- Endpoint:
- biodegradation in water and sediment: simulation tests
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Reaxys ID : 742030
- Year:
- 2 011
- Bibliographic source:
- Reaxys by Elsevier Properties SA;Susarla, Sridhar; Yonezawa, Yoshitaka; Masunaga, Shigeki; Water Research; vol. 32; nb. 3; (1998); p. 639 - 648
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Sulfate-reducing sediment samples were collected at the mouth of Tsurumi River, Japan, in 1992; in screw-top test-tubes;
GC/MS analysis was done for these samples - GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-fluoroaniline
- EC Number:
- 206-735-5
- EC Name:
- 4-fluoroaniline
- Cas Number:
- 371-40-4
- Molecular formula:
- C6H6FN
- IUPAC Name:
- 4-fluoroaniline
- Details on test material:
- - Name of test material: 4-fluoroaniline
- Molecular formula: C6H6FN
- Molecular weight: 111.12
- Substance type: Organic
- Physical state: Liquid
Constituent 1
- Radiolabelling:
- not specified
Study design
- Oxygen conditions:
- anaerobic
- Inoculum or test system:
- other: estuarine sediment slurry
- Details on source and properties of sediment:
- Sulfate-reducing sediment samples were collected at the mouth of Tsurumi River, Japan, in 1992; in screw-top test-tubes;
- Duration of test (contact time):
- 211 d
- Parameter followed for biodegradation estimation:
- test mat. analysis
Reference substance
- Reference substance:
- not specified
Results and discussion
% Degradation
- % Degr.:
- 50
- Parameter:
- test mat. analysis
- Sampling time:
- 211 d
- Remarks on result:
- other: Other details not available
Half-life of parent compound / 50% disappearance time (DT50)
- Compartment:
- sediment
- DT50:
- 211 d
- Type:
- other: First-order reaction
- Remarks on result:
- other: Other details not available
- Other kinetic parameters:
- first order rate constant
- Transformation products:
- not specified
Applicant's summary and conclusion
- Conclusions:
- The half-life of 4-fluoroaniline in an estuarine sediment slurry in anaerobic conditions is 211 days.
The first-order reaction rate constant is k=0.0033 day-1 - Executive summary:
The half-life (50% degradation) of 4-fluoroaniline in an estuarine sediment slurry in anaerobic conditions is 211 days. The first-order reaction rate constant is k=0.0033 day-1. This indicates that this substance is slowly biodegradable in sediment.
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