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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

No data on the acute toxicity to fish are available for CAS 91744-39-7. Thus, read-across from the analogue substance CAS 91744-38-6 is used.
Under the present test conditions no toxic effects caused by the test item were observed at a nominal concentration of 100 mg/L exposure medium in a limit test. None of the animals died.

Key value for chemical safety assessment

Additional information

In a 96-h acute toxicity study according to OECD 203 and GLP, zebrafish (Danio rerio) were exposed to the test substance (CAS 91744-38-6, Glycerides, C16-18 mono-, di- and tri-, hydrogenated, citrates, potassium salts) at concentrations of 0 and 100 mg/L nominal (limit test) under semi-static conditions. The 96-h LL50 based on mortality was > 100 mg/L.  No sublethal effects were observed. Based on the results of this study, the test substance would be classified as non-toxic to Danio rerio.

Although the test substance has a low water solubility and the actual test concentration was not verified, the study is classified as acceptable. In WAF procedure, suspensions of the 300 mg test substance were prepared in 3L drinking water and shaken at room temperature for 24 h. After 24 h the shaking was stopped and the solutions were filtered through paper filters directly into the test vessels used for the test. Therefore it can be concluded that the test substance is not toxic at a loading of 100 mg/L (NOELR = 100 mg/L).

Justification for read-across: The result for CAS 91744-38-6 (Glycerides, C16 -18 mono-, di- and tri-, hydrogenated, citrates, potassium salts) is used in a read-across approach for the registration of CAS 91744-39-7 (Glycerides, C16 -18 mono-, di- and tri-, hydrogenated, citrates, sodium salts

). The alkalimetal atoms are not expected to result in differences in toxicological profile and/or environmental fate and behaviour between the two substances.

Besides, water solubility of CAS 91744-38-6 is somewhat higher than water solubility of CAS 91744-39-7. Thus, potential exposure of aquatic organisms to CAS 91744-38-6 – in comparison to CAS 91744-39-7 – is higher when released to the environment and read-across from CAS 91744-38-6 to CAS 91744-39-7 is adequately protective.

For details please refer to the read-across report.