Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 200-893-9 | CAS number: 75-71-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- Not specified
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- Test result presented presented in an overview document for EPA reporting
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 978
- Report date:
- 1978
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Not specified
- Version / remarks:
- Only the results are presented in a cover letter as reporting to EPA according to Section 8 (d) of the Toxic Substances Control Act (Fed. Vol. 54, No. 38, Tuesday, February 28, 1989)
- Deviations:
- not specified
- Principles of method if other than guideline:
- EPA reporting rule on certain pesticide inert ingredients. No specific methodology is reported.
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Dichlorodifluoromethane
- EC Number:
- 200-893-9
- EC Name:
- Dichlorodifluoromethane
- Cas Number:
- 75-71-8
- Molecular formula:
- CCl2F2
- IUPAC Name:
- dichlorodifluoromethane
- Test material form:
- aerosol dispenser: not specified
- Remarks:
- migrated information: aerosol
- Details on test material:
- Not specified
Constituent 1
Test animals
- Species:
- other: species not specified.
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- Not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Details on inhalation exposure:
- Not specified
- Analytical verification of test atmosphere concentrations:
- not specified
- Remarks on duration:
- Not specified
- Concentrations:
- Not specified
- No. of animals per sex per dose:
- Not specified
- Control animals:
- not specified
- Details on study design:
- Not specified
- Statistics:
- Not specified
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- > 800 000 ppm
- Based on:
- not specified
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 3 956 155.419 mg/m³ air
- Based on:
- not specified
- Remarks on result:
- other: Conversion based on ACGIH ("2010 TLVs and BEIs, Based on the Documentation of the Threshold LImit Values for Chemical Substances and Physical Agents & Biological Exposure Indices")
- Mortality:
- No deaths
- Clinical signs:
- other: Not specified
- Body weight:
- Not specified
- Gross pathology:
- Not specified
- Other findings:
- No data
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- LC50 > 800,000 ppm. Although limited, the data set in the report indicates that the substance is not acutely harmful by inhalation exposure, and supports the weight of evidence approach for the substance. This matches the experience of handling and use of the substance. The substance is not deemed to be classified on the basis of inhalation toxicity.
- Executive summary:
LC50 > 800,000 ppm (equates to 3956155.419 mg/m3). Although limited, the data set in the report indicates that the substance is not acutely harmful by inhalation exposure, and supports the weight of evidence approach for the substance. This matches the experience of handling and use of the substance. The substance is not deemed to be classified on the basis of inhalation toxicity.
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