Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

The Heavy Oxo Fraction (Alkenes, C6-10, hydroformylation products, high-boiling, CAS#68526-82-9) is a mixture of components: A complex mixture of oxygenated hydrocarbons, primarily alcohols (C8 to C11) and aliphatic ethers (C16 to C22). All structures are branched and multi-isomeric. For the purposes of read across, data will be used from a commercial substance (Vammar D10, CAS #98072-31-2) that contains similar aliphatic ethers to Mixed HOF.


There was no evidence of skin sensitization in guinea pigs induced and challenged with CAS # 98072 -31 - 2

Migrated from Short description of key information:
Skin Sensitization – Negative for guinea pigs (OECD TG 406).

Respiratory sensitisation

Endpoint conclusion
Additional information:

There are no data which have evaluated the skin and respiratory sensitization potential of CAS # 98072 -31 - 2 in humans.  However, a skin sensitization study utilizing CAS # 98072 -31 – 2 found no indication of skin sensitization in guinea pigs.  It is presumed that CAS # 98072 -31 - 2 will not be a respiratory sensitizing agent. 

Migrated from Short description of key information:
No data

Justification for classification or non-classification

No classification for sensitization is indicated according to the general classification and labeling requirements for dangerous substances and preparations (Directive 67-548-EEC) or the classification, labeling and packaging (CLP) regulation (EC) No 1272/2008.