Registration Dossier
Registration Dossier
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EC number: 700-989-5 | CAS number: -
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Study is rated a "4" because the study predates GLP and limited details are provided.
Data source
Reference
- Reference Type:
- publication
- Title:
- A Toxicological Investigation of some Acute, Short-Term, and Chronic Effects of Administering Di-2-ethylhexyl Phthalate (DEHP) and Other Phthalate Esters
- Author:
- Lawrence WH, et al
- Year:
- 1 975
- Bibliographic source:
- Environ Res 9:1-11
Materials and methods
- Principles of method if other than guideline:
- other : not specified
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Di-''isodecyl'' phthalate
- EC Number:
- 247-977-1
- EC Name:
- Di-''isodecyl'' phthalate
- Cas Number:
- 26761-40-0
- Molecular formula:
- C28H46O4
- IUPAC Name:
- 1,2-benzenedicarboxylic acid, di-isodecyl ester
- Details on test material:
- IUCLID4 Test substance: other TS: DIDP with different CAS#
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- ICR
- Sex:
- male
Administration / exposure
- Route of administration:
- intraperitoneal
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 100 other: g/kg
Applicant's summary and conclusion
- Conclusions:
- The test substance has a low order of acute toxicity by the i.p route of exposure. The LD50 > 100 g/kg.
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