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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Data is from experimental study report
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
Water soluility of test chemical was determined by shake flask method. In this case, weight of the chemical substance dissolved in water to form a homogeneous solution of the solute in the solvent

GLP compliance:
no
Type of method:
other: shake flask method
Key result
Water solubility:
1 000 mg/L
Conc. based on:
test mat.
Temp.:
30 °C
pH:
6.6
Remarks on result:
other: Soluble in water

Quantity of the Test Substance

(mg or ml)

 

Volume of water to be added

(mL)

Temperature at which the testing performed

(°C)

Procedures undertaken

Water solubility Value / Range

(in mg/L)

pH of test solution

 

100 mg

 

 

100 ml

 

30°C

 

Mechanical Stirring

24Hrs

 

1000mg/l

 

 

 

6.6

 

Membrane Filtration

Not Applicable

Hot Air Oven Drying/

Air Drying

 Not Applicable

Conclusions:
The water solubility determination of test substance was done as per the shake flask method. The solubility was determined to be 1000 mg/l 30 deg C.
Executive summary:

The water solubility determination of test substance was done as per the shake flask method. The solubility was determined to be 1000 mg/l 300C.

Description of key information

The water solubility determination of test substance was done as per the shake flask method. The solubility was determined to be 1000 mg/l at 300C.

Key value for chemical safety assessment

Water solubility:
1 000 mg/L
at the temperature of:
30 °C

Additional information

The water solubility determination of test substance was done as per the shake flask method. The solubility was determined to be 1000 mg/l at 300C.

From other experimental report, water solubility of test chemical was determined to be 4000 mg/L at 28°C indicating that the substance is soluble in water.