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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
other: publication
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary literature , no details described

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1991

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified
Test type:
other: acute inhalation (no details)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
no data

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals and environmental conditions:
no data

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
not specified
Details on inhalation exposure:
no data
Analytical verification of test atmosphere concentrations:
not specified
Remarks on duration:
no data
Concentrations:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified
Details on study design:
no data
Statistics:
no data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
6 095 ppm
Mortality:
no data
Clinical signs:
other: no data
Body weight:
no data
Gross pathology:
no data
Other findings:
no data

Any other information on results incl. tables

- rats tolerate exposure to concentrated vapour for up to 15 minutes (no death)

- exposure of 8000 ppm (4 hours): 4 of 6 rats died

Applicant's summary and conclusion