Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In the key studies, skin sensitising potential of other gas oils was investigated in male Hartley guinea pigs that were dermally exposed to hydrodesulfurised middle distillate (Klimisch scores = 2, API 1984a,b). In the first key study, the test material was administered at a concentration of 25% v/v in paraffin oil for the induction phase and at 10% v/v in paraffin oil for the challenge application. The test material induced slight erythema but no oedema following the challenge application. In the second study, the test material was administered undiluted for the induction phase and at a concentration of 10% v/v in paraffin oil for the challenge application. The test material elicited well-defined erythema and slight oedema during the induction phase but no response upon challenge. Based on the results of these studies, neither sample of hydrodesulfurised middle distillate was a dermal sensitiser in guinea pigs.


Migrated from Short description of key information:
Skin sensitisation studies indicate that other gas oils do not induce or elicit allergic skin reactions in the guinea pig (OECD 406).

Justification for classification or non-classification

Other Gas Oils do not meet the criteria for classification as sensitising to the skin according to EU CLP Regulation (EC No. 1272/2008).