Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
ECB
Year:
2000
Bibliographic source:
IUCLID4 data set

Materials and methods

Test guideline
Guideline:
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N'-ethylenedi(stearamide)
EC Number:
203-755-6
EC Name:
N,N'-ethylenedi(stearamide)
Cas Number:
110-30-5
Molecular formula:
C38H76N2O2
IUPAC Name:
N,N'-ethylenedi(stearamide)

Test animals / tissue source

Species:
rabbit
Strain:
other: New Zealand

Test system

Vehicle:
other: polyethylene glycol
Amount / concentration applied:
100 mg substance in 0.4 ml polyethylene glycol (approx. 25%)
Duration of treatment / exposure:
eyes were rinsed after 24h
Observation period (in vivo):
3 days
Number of animals or in vitro replicates:
6

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Max. score:
110
Reversibility:
fully reversible
Remarks on result:
other: slightly irritating

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU