Registration Dossier

Diss Factsheets

Administrative data

Description of key information

The key acute oral study (Chevron Phillips Chemical Company, 2010) was conducted in female rats according to OECD 423 using the Acute Toxic Class Method. Clinical signs of toxicity but no deaths occurred at 2000 mg/kg bw. There was no overt toxicity at the lower dose of 300 mg/kg bw. 
No other acute studies were evaluated.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
2 000 mg/kg bw

Additional information

Only one acute study was available for evaluation. This acute oral study was a guideline study (reliability 1, with GLP).

Justification for classification or non-classification

The available data do not support classification for acute oral effects (Regulation (EC) No 1272/2008; Directive 67/548/EEC).