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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

The inhibitory effect of DNBP on the respiration of activated sludge was examined in an experiment conducted in accordance with OECD 209, EU method C.11 and US EPA OPPTS 850.6800 guidelines.
The effect of the test item on the respiration of activated sewage sludge micro-organisms gave a 3-Hour EC50 of 130 mg/l, 95% confidence limits 100 - 170 mg/l. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 22 mg/l.

Key value for chemical safety assessment

EC50 for microorganisms:
130 mg/L
EC10 or NOEC for microorganisms:
22 mg/L

Additional information

A reliability rating of 1 was assigned to the key study, according to the criteria of Klimisch, 1997 as the study was conducted in accordance with recognised guidelines and GLP.