Registration Dossier
Registration Dossier
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EC number: 219-847-4 | CAS number: 2550-26-7
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
No valid guideline studies covering this endpoint are available
Key value for chemical safety assessment
Additional information
Studying the toxicity to terrestrial plants is not a testing requirement for substances in the tonnage band 10 to 100 tonnes per year. Supporting information on in-vitro testing of toxicity of 4-phenylbutan-2-one to terrestrial plants is available which gives limited evidence that the substance may inhibit the germination of terrestrial plants. The study of Reynolds (1989) showed that germination of lettuce seeds was inhibited by 50% at a nominal test concentration of 99.3 mg/L over a period of 72 hours when compared to the germination obtained with water in the experimental control. The observation period in this study was much shorter than required in the testing guideline. In addition, it remains unclear if the control fulfilled the validity criteria described in the testing guideline. The experimental result therefore is considered as not reliable. Further studies showed that germination of seeds of rice, radish, monochoria and barnyardgrass was inhibited by varying degrees at a nominal test concentration of 100 mg/L over a period of 5 days (Khanh et al. 2008). Also these data were obtained from studies that are considered as not reliable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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