Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 219-847-4 | CAS number: 2550-26-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
No valid guideline studies covering this endpoint are available
Key value for chemical safety assessment
Additional information
Studying the toxicity to terrestrial plants is not a testing requirement for substances in the tonnage band 10 to 100 tonnes per year. Supporting information on in-vitro testing of toxicity of 4-phenylbutan-2-one to terrestrial plants is available which gives limited evidence that the substance may inhibit the germination of terrestrial plants. The study of Reynolds (1989) showed that germination of lettuce seeds was inhibited by 50% at a nominal test concentration of 99.3 mg/L over a period of 72 hours when compared to the germination obtained with water in the experimental control. The observation period in this study was much shorter than required in the testing guideline. In addition, it remains unclear if the control fulfilled the validity criteria described in the testing guideline. The experimental result therefore is considered as not reliable. Further studies showed that germination of seeds of rice, radish, monochoria and barnyardgrass was inhibited by varying degrees at a nominal test concentration of 100 mg/L over a period of 5 days (Khanh et al. 2008). Also these data were obtained from studies that are considered as not reliable.
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