Registration Dossier
Registration Dossier
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EC number: 701-269-3 | CAS number: -
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The key study corresponding OECD 216 guideline was performed to GLP using the read-across substance (Chastenet, 2018). The rate of nitrate formation in treated samples compared with the rate in the controls, and the percent deviation of the treated from the control were calculated. No dose-response relationship could be observed and the EC10, EC50 values could not be calculated. No inhibitory effect was observed up to 401.6 mg test item/kg soil dry weight 28 days after application. The NOEC is therefore considered to be equal to or greater than 401.6 mg test item/kg soil dry weight. In compliance with guideline OECD 216, the study can be regarded to be valid, since the variation of nitrate-N content between replicate control samples was less than 15%. It is concluded that no toxicity was observed following exposure to the read-across substance CAS 100454 -48 -0.
Key value for chemical safety assessment
- Long-term EC10 or NOEC for soil microorganisms:
- 401.6 mg/kg soil dw
Additional information
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