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Diss Factsheets
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EC number: 205-569-0 | CAS number: 142-88-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish
The lethal concentration (LC50) for piperazine adipate for Oncorhynchus mykiss at 96 hours is estimated to be 134.66 mg/L. Based on this value it can be concluded that piperazine adipate is not toxic to aquatic environment based the criteria given by CLP regulation.
Long-term toxicity to fish
According to column I of annex IX , Long-term toxicity testing on fish need not to be conducted as information on short term toxicity effect is already provided as part of Annex VIII requirements. Therefore this study was considered to be waived.
Short-term toxicity to aquatic invertebrates
The effective concentration (EC50) for piperazine adipate for Daphnia magna at 48 hours is estimated to be 201.06 mg/L for intoxication effect. Based on this value it can be concluded that piperazine adipate is not toxic to aquatic environment based the criteria given by CLP regulation.
Long-term toxicity to aquatic invertebrates
According to column I of annex IX ; Long-term toxicity testing on invertebrate (species : Daphnia) need not to be conducted as information on short term toxicity to aquatic invertebrates is already provided as a part of Annex VII requirements. Therefore this study was considered for waiver.
Toxicity to aquatic algae and cyanobacteria
The effective concentration (EC50) for piperazine adipate for Pseudokirchneriella subcapitata at 72 hours is estimated to be 119.68 mg/L for effect on growth. Based on this value it can be concluded that piperazine adipate is not toxic to aquatic environment based the criteria given by CLP regulation.
Toxicity to microorganisms
The growth inhibition concentration (IGC50) for piperazine adipate for Tetrahymena pyriformis at 48 hours is estimated to be 916.19 mg/L for effect on growth. Based on this value it can be concluded that piperazine adipate is not toxic to aquatic environment based the criteria given by CLP regulation
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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