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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Remarks:
Study on behalf of competent authorities of Japan
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
not specified
GLP compliance:
yes
Type of method:
flask method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
photometric method
Key result
Type:
log Pow
Partition coefficient:
1.83
Temp.:
25 °C
pH:
6.3
Type:
log Pow
Partition coefficient:
>= 1.66 - <= 2.09
Temp.:
25 °C
pH:
6.3
Details on results:
The results are rounded to three significant digits according to the method of JIS Z 8401-1961.
Conclusions:
The logPow was determined to be 1.83 at 25°C.
Executive summary:

The partition coefficient of 3.5-Xylidine was evaluated in an GLP study according to OECD Guideline 107. The logPow was determined to be in the range of 1.66 - 2.09 and the mean measured logPow was 1.83 at 25°C.

Description of key information

OECD 107, logPow at 25°C was 1.83 +/- 0.18

Key value for chemical safety assessment

Log Kow (Log Pow):
1.83
at the temperature of:
25 °C

Additional information