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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Xylidine, BUA Stoffbericht 161
Year:
1994
Bibliographic source:
BUA, Beratergremium für umweltrelevante Altstoffe (BUA) der Gesellschaft Deutscher Chemiker, S.Hirzel Verlag 1995
Reference Type:
publication
Title:
Acute toxicity and skin corrosion data for some organic and inorganic compounds and aqeous solutions.
Author:
Vernot et al.
Year:
1977
Bibliographic source:
Toxicol. Appl. Pharmacol. 42, 417-423 (1977)

Materials and methods

Test guideline
Guideline:
other: no data
GLP compliance:
not specified
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
3,5-xylidine
EC Number:
203-607-0
EC Name:
3,5-xylidine
Cas Number:
108-69-0
Molecular formula:
C8H11N
IUPAC Name:
3,5-dimethylaniline

Test animals

Species:
rat
Strain:
not specified
Sex:
male

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
710 mg/kg bw
Based on:
test mat.
95% CL:
>= 470 - <= 1 070

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU