Registration Dossier
Registration Dossier
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EC number: 266-340-9 | CAS number: 66402-68-4 This category encompasses the various chemical substances manufactured in the production of ceramics. For purposes of this category, a ceramic is defined as a crystalline or partially crystalline, inorganic, non-metallic, usually opaque substance consisting principally of combinations of inorganic oxides of aluminum, calcium, chromium, iron, magnesium, silicon, titanium, or zirconium which conventionally is formed first by fusion or sintering at very high temperatures, then by cooling, generally resulting in a rigid, brittle monophase or multiphase structure. (Those ceramics which are produced by heating inorganic glass, thereby changing its physical structure from amorphous to crystalline but not its chemical identity are not included in this definition.) This category consists of chemical substances other than by-products or impurities which are formed during the production of various ceramics and concurrently incorporated into a ceramic mixture. Its composition may contain any one or a combination of these substances. Trace amounts of oxides and other substances may be present. The following representative elements are principally present as oxides but may also be present as borides, carbides, chlorides, fluorides, nitrides, silicides, or sulfides in multiple oxidation states, or in more complex compounds.@Aluminum@Lithium@Barium@Magnesium@Beryllium@Manganese@Boron@Phosphorus@Cadmium@Potassium@Calcium@Silicon@Carbon@Sodium@Cerium@Thorium@Cesium@Tin@Chromium@Titanium@Cobalt@Uranium@Copper@Yttrium@Hafnium@Zinc@Iron@Zirconium
Bioaccumulation: terrestrial
Administrative data
Link to relevant study record(s)
Description of key information
Bioaccumulation is not expected to be relevant for the test substance.
Key value for chemical safety assessment
Additional information
There are no studies available for “Reaction product of thermal process between 1000°C and 2000°C of mainly aluminium oxide and calcium oxide based raw materials with at least CaO+Al2O3 >80% , in which aluminium oxide and calcium oxide in varying amounts are combined in various proportions into a multiphase crystalline matrix”. As this substance is an UVCB substance with aluminium oxide (AL2O3) and calcium oxide (CaO) as main constituents, justification based on both main components were taken into account.
Aluminium compounds:
The available evidence shows the absence of aluminium biomagnification across trophic levels both in aquatic and terrestrial food chains. The existing information suggests not only that aluminium does not biomagnify, but rather that it tends to exhibit biodilution at higher trophic levels in the food chain. More detailed information can be found in the attached document (White paper on waiving for secondary poisoning for Al & Fe compounds final report 25-01-2010. pdf).
Calcium compounds:
In soil, exposure to calcium oxide actually comes down to exposure to calcium and hydroxyl ions. There will be no intake of calcium oxide as such from soil, nor will calcium oxide prevail under its original form in the organisms. Moreover, both the intake of the essential element calcium and the internal pH of an organism are actively regulated (homeostasis). Therefore, this endpoint is considered not to be relevant for calcium oxide. However, the results of one study were considered useful as supporting information. This study (Mora et al., 1999) investigated the transfer of calcium from soil to plants after soil amendment of calcitic and/or dolomitic limestone. BSAF factors were calculated for calcium.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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