Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: PEER REVIEWED

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Ambient Water Quality Criteria Doc: 2,4-Dimethylphenol
Author:
USEPA
Year:
1980
Bibliographic source:
p.C-12 (1980) EPA 440/5-80-044
Reference Type:
publication
Title:
Gigiena Truda i Professional'nye Zabolevaniya
Year:
1974
Bibliographic source:
Labor Hygiene and Occupational Diseases. Vol. 18(2), Pg. 58, 1974.
Reference Type:
secondary source
Title:
No information
Author:
Database
Year:
2015
Bibliographic source:
Gestis-Database of Institut für Arbeitsschutz der deutschen gesetzlichen Unfallversicherungen

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: no data
GLP compliance:
not specified
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
2,4-xylenol
EC Number:
203-321-6
EC Name:
2,4-xylenol
Cas Number:
105-67-9
Molecular formula:
C8H10O
IUPAC Name:
2,4-dimethylphenol

Test animals

Species:
rat

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 040 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion