Registration Dossier
Registration Dossier
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EC number: 225-791-1 | CAS number: 5080-22-8
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
A 1st tier hydrolysis study was conducted for IPHA following OECD 111 guidelines. Hydrolysis half-life was 6 days at pH 4, <0.5day at pH 7, and <1h at pH 9.
Key value for chemical safety assessment
Additional information
A 1sttier hydrolysis study was conducted for IPHA in accordance with the test procedure described in the OECD “Hydrolysis as a Function of pH” guideline method 111. The test substance showed increasing hydrolysis rates with a rise in pH. Since hydrolysis of IPHA at 50 ºC exceeded 10% after 5 days at each pH tested, the compound is considered to be hydrolytically unstable at pH 4, 7, and 9.
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