Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

Currently viewing:

Administrative data

Endpoint:
skin irritation / corrosion, other
Remarks:
no data
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
Data are used by the OECD Toolbox and can be considered as reliable peer-reviewed data.

Data source

Reference
Reference Type:
other: Danish EPA
Title:
Multicase model
Author:
HSDB
Year:
2000
Bibliographic source:
Data from RTECS nov. 2000, HSDB nov. 2000, and 22. Amendment of EU Annex I
Report date:
2000

Materials and methods

Principles of method if other than guideline:
No data on guideline
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
N-methylaniline
EC Number:
202-870-9
EC Name:
N-methylaniline
Cas Number:
100-61-8
Molecular formula:
C7H9N
IUPAC Name:
N-methylaniline

Test animals

Species:
other: no data
Strain:
not specified

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified
Duration of treatment / exposure:
No data
Observation period:
No data
Number of animals:
No data

Results and discussion

In vivo

Results
Irritation parameter:
other: Multicase model
Basis:
other: QSAR
Time point:
other: Not applicable
Score:
-1
Reversibility:
no data
Remarks on result:
other: Negative for skin irritation.

Applicant's summary and conclusion

Interpretation of results:
other: negative
Remarks:
Criteria used for interpretation of results: other: Danish EPA
Conclusions:
The substance is expected as non-irritating to skin.