Registration Dossier
Registration Dossier
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EC number: 200-756-3 | CAS number: 71-55-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
In a recent (Pelcot 2009) Guinea pig sensitisation study (OECD 406, Magnusson and Kligman), 1,1,1-trichloroethane (not stabilized) was used in the challenge phase at a concentration of 50 % (w/w); a positive skin reaction was recorded in 3/20 guinea pigs. The test substance was classified as a non-sensitiser to the skin.
Migrated from Short description of key information:
In a recent (2009) Guinea pig sensitisation study (OECD 406, Magnusson and Kligman), 1,1,1-trichloroethane (not stabilized) was used in the challenge phase at a concentration of 50 % (w/w); a positive skin reaction was recorded in 3/20 guinea pigs. The test substance was classified as a non-sensitiser to the skin.
Justification for classification or non-classification
1,1,1 -trichloroethane has been evaluated in an OECD 406 Guinea pig sensitisation study and found to be non-sensitizer. It therefore does not warrent classification.
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