Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
genetic toxicity in vitro
Remarks:
Type of genotoxicity: other: chromosome damage, genotoxicity, mutagenicity
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
2010
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Principles of method if other than guideline:
Software used: DEREK Nexus, version 2.0.0, 2010 LHASA Ltd, Leeds, UK
GLP compliance:
no
Type of assay:
other: QSAR using Derek Nexus, version 2.0.0

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethyl 2-cyano-3-ethoxyacrylate
EC Number:
202-299-5
EC Name:
Ethyl 2-cyano-3-ethoxyacrylate
Cas Number:
94-05-3
Molecular formula:
C8H11NO3
IUPAC Name:
ethyl 2-cyano-3-ethoxyacrylate

Results and discussion

Test results
Species / strain:
not specified
Metabolic activation:
not specified
Genotoxicity:
other: no alert
Cytotoxicity / choice of top concentrations:
not specified

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information):
other: no alert

No alert for chromosome damage, genotoxicity and mutagenicity of the Ethyl- 2-cyano-3-ethoxyacrylate was detected by DEREK Nexus version 2.0.0.