Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
sub-chronic toxicity: oral
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2014
Bibliographic source:
OECD Toolbox v3.2

Materials and methods

Test guideline
Guideline:
other: read across (Ecosar class poly phenols, strict)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,4-dihydroxybenzophenone
EC Number:
205-029-4
EC Name:
2,4-dihydroxybenzophenone
Cas Number:
131-56-6
Molecular formula:
C13H10O3
IUPAC Name:
4-benzoylbenzene-1,3-diol

Test animals

Species:
rat
Sex:
male/female

Administration / exposure

Route of administration:
oral: unspecified
Duration of treatment / exposure:
90d

Results and discussion

Effect levels

Dose descriptor:
NOAEL
Effect level:
236 mg/kg bw/day (nominal)
Based on:
test mat.
Sex:
male/female
Basis for effect level:
other: 90d test, oral, rat; undefined organ, undefined (systemic) effect

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion