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Short-term toxicity to aquatic invertebrates

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Description of key information

48h EC50 (Daphnia magna, immobilization) > 100 mg/L (nominal concentration, OECD 202)

Key value for chemical safety assessment

Additional information

The key, GLP short-term toxicity test with Daphnia magna was performed according to OECD 202 guideline (Neven 1993). Daphnids were exposed under semi-static conditions to five test concentrations up to 100 mg/L (nominal concentrations in agreement with the measured ones). Based on mobility of daphnids, the 48-hour EC50 value was determined to be above 100 mg/L (nominal concentration). Moreover, three supporting 24-hour tests with Daphnia magna are available for C8AS Na (CAS 142-31-4). The non-GLP study of Richterich (2001) was performed according to OECD 202 guideline with Daphnia magna. Daphnids were exposed in a static test to fourteen different test concentrations up to the nominal concentration of 1000 mg/L. Analytical measurements are not available. The 24-hour EC50 value based on mobility was above 240 mg/L (nominal concentration). Lundahl (1978) reports a non-GLP test with Daphnia magna which was performed according to AFNOR T.90301 (1974) method. The result showed that the 24-hour EC50 value was 4350 mg/L. No analytical measurements were given. The last supporting study followed a method described by "Norme Francaise Homologue, 1983, NF T90-31" (Sanchez Leal 1991). The 24-hour test with Daphnia magna resulted in the EC50 value above 900 mg/L (nominal concentration, analytical measurements are not provided).

Based on the presented results it can be concluded that the 48-hour EC50 value to aquatic invertebrates is above 100 mg/L.

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