Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Absorption rate - oral (%):
100
Absorption rate - dermal (%):
100
Absorption rate - inhalation (%):
100

Additional information

Limited information are available on toxicokinetics, metabolism and distribution of 11-aminoundecanoic acid. Five F-344 rats of each sex were each dosed orally (stomach tube) with 1 mCi of 11 -14C-aminoundecanoic acid. In the 24 hours following administration of the chemical, urine and feces were collected. Within 24 hours of the oral administration of 11 -14C-aminoundecanoic acid, approximately 80 % of radioactivity was excreted in urine in the form of metabolites and minor amounts of 14CO2 were produced by metabolism of 11 -14C-aminoundecanoic acid. Under the conditions of this test, results indicated that 11-aminoundecanoic acid is rapidly and extensively absorbed by rats after an oral administration, distributed in the body and rapidly excreted mainly via urine.