Registration Dossier
Registration Dossier
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EC number: 927-721-1 | CAS number: 1178858-40-6
Guidance on Safe Use
Administrative data
First-aid measures
Description of First Aid Measures
Eye Contact: Immediately flush eyes with water for at least 15 minutes. If irritation occurs or persists, get medical attention.
Skin Contact: Wash skin with soap and water. Remove contaminated clothing and shoes. This material may not be completely removed by conventional laundering. Consult professional laundry service.Do not home launder. If irritation occurs or persists, get medical attention.
Ingestion: Get medical attention immediately. Do not induce vomiting unless directed by medical personnel. Never give anything by mouth to an unconscious person.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. Get medical attention immediately.
Most Important Symptoms and Effects, Both Acute and Delayed
Symptoms and Effects of Exposure: For information on potential signs and symptoms of exposure, See Hazards Identification and/or Toxicological Information.
Medical Conditions Aggravated by Exposure: None known
Indication of the Immediate Medical Attention and Special Treatment Needed
Notes to Physician: None
Fire-fighting measures
Extinguishing Media: Use carbon dioxide, dry chemical, or water spray.
Special Hazards Arising from the Substance or Mixture
Hazardous Combustion Products: Emits toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides, and other fluorine- and sulfur-containing compounds.
Fire / Explosion Hazards: Fine particles (such as dust and mists) may fuel fires/explosions.
Advice for Fire-Fighters
Wear approved positive pressure, self-contained breathing apparatus and full protective turn out gear. Evacuate area and fight fire from a safe distance.
Accidental release measures
Personal Precautions, Protective Equipment and Emergency Procedures
Personnel involved in clean-up should wear appropriate personal protective equipment. Minimize exposure.
Environmental Precautions
Place waste in an appropriately labeled, sealed container for disposal. Care should be taken to avoid environmental release.
Methods and Material for Containment and Cleaning Up
Measures for Cleaning / Collecting: Contain the source of spill if it is safe to do so. Collect spilled material by a method that controls dust generation. A damp cloth or a filtered vacuum should be used to clean spills of dry solids. Clean spill area thoroughly.
Additional Consideration for Large Spills: Non-essential personnel should be evacuated from affected area. Report emergency situations immediately. Clean up operations should only be undertaken by trained personnel.
Handling and storage
Precautions for Safe Handling
Ground and bond all bulk transfer equipment. Avoid open handling. Minimize dust generation. Use local exhaust ventilation or perform work under fume hood/fume cupboard. Avoid inhalation and contact with skin, eye, and clothing. When handling, use appropriate personal protective equipment. Wash hands and any exposed skin after removal of PPE. Releases to the environment should be avoided. Review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure or environmental releases. Potential points of process emissions of this material to the atmosphere should be controlled with dust collectors, HEPA filtration systems or other equivalent controls.
Conditions for Safe Storage, Including any Incompatibilities
Storage Conditions: Keep container tightly closed when not in use. Store out of direct sunlight in a well ventilated area at room temperature.
Specific end use(s): No data available
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- UN 2811
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Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- UN 2811
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Marine transport (UN RTDG/IMDG)
- UN number:
- UN 2811
Shipping information
- Proper shipping name and description:
- Toxic solid, organic, n.o.s. (bis-triazole)
- Chemical name:
- (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- UN 2811
Shipping information
- Proper shipping name and description:
- Toxic solid, organic, n.o.s. (bis-triazole)
- Chemical name:
- (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate
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Exposure controls / personal protection
Control Parameters
UK-109,496-BV
Pfizer OEL TWA-8 Hr: 0.1 mg/m³
Analytical Method: Analytical method available. Contact Pfizer Inc for further information.
Exposure Controls
Engineering Controls: Engineering controls should be used as the primary means to control exposures. Use process containment, local exhaust ventilation, or other engineering controls to maintain airborne levels below recommended exposure limits.
Personal Protective Equipment: Refer to applicable national standards and regulations in the selection and use of personal protective equipment (PPE).
Hands: Wear impervious gloves as minimum protection.
Eyes: Wear safety glasses as minimum protection.
Skin: Wear impervious protective clothing when handling this compound.
Respiratory protection: If the applicable Occupational Exposure Limit (OEL) is exceeded, wear an appropriate respirator with a protection factor sufficient to control exposures to below the OEL.
Stability and reactivity
Reactivity: No data available
Chemical Stability: Stable at ambient temperatures
Possibility of Hazardous Reactions Oxidizing Properties: No data available
Conditions to Avoid: Eliminate possible ignition sources (e.g., heat, sparks, flame, impact, friction, electrostatic discharge).
Incompatible Materials: As a precautionary measure, keep away from strong oxidizers
Hazardous Decomposition Products: Thermal decomposition products include oxides of nitrogen, carbon monoxide, carbon dioxide, and halogen containing gases.
Disposal considerations
Waste Treatment Methods: Dispose of waste in accordance with all applicable laws and regulations. Member State specific and Community specific provisions must be considered. Considering the relevant known environmental and human health hazards of the material, review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure and environmental release. It is recommended that waste minimization be practiced. The best available technology should be utilized to prevent environmental releases. This may include destructive techniques for waste and wastewater.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
