3,7-dimethyloct-6-en-1-yn-3-ol

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Study period:

07.11.1988 - 18.11.1988

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: non GLP study, non OECD guideline study

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1988

Report date:

1988

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: DIN 38412 L 9

Deviations:

no

Principles of method if other than guideline:

Not available

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

3,7-dimethyloct-6-en-1-yn-3-ol

EC Number:

249-482-6

EC Name:

3,7-dimethyloct-6-en-1-yn-3-ol

Cas Number:

29171-20-8

Molecular formula:

C10H16O

IUPAC Name:

3,7-dimethyloct-6-en-1-yn-3-ol

Details on test material:

- Name of test material (as cited in study report): Dehydrolinalool
Stability under test conditions: not available

Specific details on test material used for the study:

Details on properties of test surrogate or analogue material (migrated information):
Not available

Sampling and analysis

Analytical monitoring:

no

Details on sampling:

Not available

Test solutions

Vehicle:

yes

Details on test solutions:

est concentrations (nominal): 7.8, 15.6, 31.25, 62.5, 125 mg/L

Test organisms

Test organisms (species):

Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Details on test organisms:

TEST ORGANISM
- Common name: Scenedesmus subspicatus
- Source (laboratory, culture collection): Algensammlung Göttingen, SAG 86.81


ACCLIMATION
- Acclimation period: 3 days
- Culturing media and conditions (same as test or not): no data
- Any deformed or abnormal cells observed: no data

Study design

Test type:

static

Water media type:

freshwater

Total exposure duration:

96 h

Post exposure observation period:

No data

Test conditions

Hardness:

Not available

Test temperature:

20.0 °C

pH:

7.24 - 8.5

Dissolved oxygen:

not available

Salinity:

not applicable

Nominal and measured concentrations:

Nominal: 7.81, 15.63, 31.25, 62.5, 125 mg/L

Details on test conditions:

- Adjustment of pH: no
- Chlorophyll measurement: fluorimeter
TEST CONCENTRATIONS

- Test concentrations: 7.81 -125 mg/L

Reference substance (positive control):

not specified

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

42.1 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

biomass

Effect concentrations 2

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

53.5 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth rate

Effect concentrations 3

Duration:

72 h

Dose descriptor:

EC10

Effect conc.:

30.4 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

biomass

Effect concentrations 4

Duration:

72 h

Dose descriptor:

EC10

Effect conc.:

34.2 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth rate

Details on results:

- Exponential growth in the control (for algal test): yes
- Observation of abnormalities (for algal test): not available

Results with reference substance (positive control):

No data

Reported statistics and error estimates:

No data

Any other information on results incl. tables

Biomass:                                             

EC10 : 30.4 mg/L

EC50 : 42.1 mg/L

Growth rate:

EC 10 : 34.2 mg/L

EC 50 : 53.5 mg/

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

EC50 of inhibition on biomass and growth rate of this fresh water algae species were determined at 42.1 mg/l and 53.5 mg/l, respectively .

Executive summary:

The influence of the test item Dehydrolinalool on the growth of the green algal species Scenedesmus subspicatus was investigated in a 96-hour static test according to the DIN 38412 L 9 guideline. EC 50 of biomass/growth rate of this fresh water algae species was determined to be 42.1 / 53.5 mg/l in 72 hour period.