Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

fish early-life stage toxicity
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:

Description of key information

No data available. Considering all relevant information available, long-term toxicity for fish is not expected.

Key value for chemical safety assessment

Additional information

No long-term fish studies are available for 2-amino-2-ethyl-1,3-propanediol (AEPD). Short-term studies available for fish, daphnia and algae, all indicate a low potential for aquatic toxicity, with LC/EC50 values between 460 and 668 mg/L. Furthermore, the substance is not expected to remain in the aquatic environment, since it is rapidly biodegradable. Bioaccumulation is unlikely, due to the low log Kow value. Additionally, long-term NOECs of 3.99 mg/L and 31.3 mg/L have been determined for Dapnia magna and Pseudokirchneriella subcapitata, respectively. Based on this information and for reasons of animal welfare, long-term testing on fish is not proposed.