Registration Dossier

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Administrative data

Key value for chemical safety assessment

Additional information

Chloroethylene has been tested bothin vitroandin vivofor mutagenic activity providing positive results. Additionally, the QSAR modelling predicts the mutagenic activity of this substance.

 

Based on the data summarised here it is proposed to classify chloroethylene as Mutagen Category 1B, H340: May cause genetic defects

Endpoint Conclusion: Adverse effect observed (positive)

Justification for classification or non-classification

Chloroethylene has been tested bothin vitroandin vivofor mutagenic activity providing positive results. Additionally, the QSAR modelling predicts the mutagenic activity of this substance.

 

Based on the data summarised here it is proposed to classify chloroethylene as Mutagen Category 1B, H340: May cause genetic defects