Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 617-345-3 | CAS number: 82543-14-4
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 2000-08-25
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Pretest quality data
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Screening method based on the detection of the beginning of precipitate formation upon
portion-wise addition of an organic solution of the respective test substance under continuous
stirring into an excess volume of water while maintaining a temperature range of 25 to 30 °C. - GLP compliance:
- yes
Test material
- Reference substance name:
- 5-hydroxy-15β,16β-methylene-3β-pivaloyloxy-5β-androst-6-en-17-one
- EC Number:
- 617-345-3
- Cas Number:
- 82543-14-4
- Molecular formula:
- C25H36O4
- IUPAC Name:
- 5-hydroxy-15β,16β-methylene-3β-pivaloyloxy-5β-androst-6-en-17-one
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 0.006 g/L
- Temp.:
- 25 °C
- Remarks on result:
- other: pH not measured
Applicant's summary and conclusion
- Executive summary:
The water solubility of ZK 90504 was determined in "pretest quality" to be
0.006 g/L
using a screening method based on the detection of the beginning of precipitate formation upon
portion-wise addition of an organic solution of the respective test substance under continuous
stirring into an excess volume of water while maintaining a temperature range of 25 to 30 °C.
Due to the specifics of the screening method, the above value is expected to represent an upper
limit which should not be exceeded by the test substance in its crystalline form.
The solubility of ZK 90504 is well below the lower limit set by the VCI guidance of 0.1 g/l.
Therefore no further measurements are necessary within the scope of this study.
ZK 90504 is to be considered as practically insoluble or insoluble in water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
