Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 449-980-5 | CAS number: -
Specific investigations: other studies
Administrative data
- Endpoint:
- specific investigations: other studies
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
- Principles of method if other than guideline:
- Test procedure:
OECD Guideline for the Testing of Chemicals No. 429 "Skin
Sensitisation: Local Lymph Node Assay" (adopted 24 April
2002).
Results and discussion
- Details on results:
- Following a preliminary screening test, three groups, each
of five animals, were treated with 50 µl (25 µl per ear) of
the test material as a solution in dimethyl sulphoxide at
concentrations of 10%, 5% and 2.5% w/w. A further group of
five animals was treated with dimethyl sulphoxide.
The Stimulation Index (SI) expressed as the mean radioactive
incorporation for each treatment group divided by the mean
radioactive incorporation of the vehicle control group are
as follows:
Conc. (%w/w) in Stimulation Index Result
Dimethyl Sulphoxide (SI)
2.5 0.70 Negative
5 0.69 Negative
10 1.33 Negative
The test material was considered to be a non-sensitiser
under the conditions of the test.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
