Registration Dossier

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study, basic data given

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1989
Report date:
1989
Reference Type:
secondary source
Title:
2,3,4-TRICHLORO-1-BUTENE
Author:
ECB
Year:
2000
Bibliographic source:
ECB IUCLID dataset
Reference Type:
secondary source
Title:
2,3,4-TRICHLORO-1-BUTENE - CAS No: 2431-50-7
Author:
OECD
Year:
1993
Bibliographic source:
Screening Information Data Set (SIDS) of OECD High Production Volume Chemicals Programme, (1993)

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2,3,4-trichlorobut-1-ene
EC Number:
219-397-9
EC Name:
2,3,4-trichlorobut-1-ene
Cas Number:
2431-50-7
Molecular formula:
C4H5Cl3
IUPAC Name:
2,3,4-trichlorobut-1-ene

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no
Details on test solutions:
directly weighted into the test vessels

Test organisms

Test organisms (species):
activated sludge
Details on inoculum:
- Laboratory culture: yes, laboratory treatment plant

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
3 h

Test conditions

Nominal and measured concentrations:
Nominal concentrations: 100, 180, 320, 560, 1000, 10000 mg/L
Details on test conditions:
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of medium: according to guideline (nutrient medium: ISO 8192-1986)
Reference substance (positive control):
yes
Remarks:
3,5-dichlorphenol

Results and discussion

Effect concentrationsopen allclose all
Duration:
3 h
Dose descriptor:
EC10
Effect conc.:
59.7 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
394 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate
Duration:
3 h
Dose descriptor:
other: EC5
Effect conc.:
35 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate

Applicant's summary and conclusion