Registration Dossier

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only short abstract available

Data source

Reference
Reference Type:
other: Abstract
Title:
Comparative toxicity of chlorinated hydrocarbons from the production of chloroprene rubber Nairit PNK.
Author:
Gizhlaryan
Year:
1974
Bibliographic source:
Chemical Abstracts, 80

Materials and methods

Principles of method if other than guideline:
Only short abstract available
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,3,4-trichlorobut-1-ene
EC Number:
219-397-9
EC Name:
2,3,4-trichlorobut-1-ene
Cas Number:
2431-50-7
Molecular formula:
C4H5Cl3
IUPAC Name:
2,3,4-trichlorobut-1-ene

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Results and discussion

Any other information on results incl. tables

Topical application of trichlorobutene to the eye produced purulent conjunctivitis in rabbits.

Applicant's summary and conclusion

Interpretation of results:
irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU