Registration Dossier
Registration Dossier
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EC number: 918-973-3 | CAS number: 1174522-45-2
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
C14-20 Aliphatics (≤2% aromatic) are hydrocarbon UVCBs. Standard tests for this endpoint are intended for single substances and are not appropriate for these complex substances. However, this endpoint has been calculated for representative hydrocarbon structures using the BCFWIN v2.16 model within EPISuite 3.12 as input to the hydrocarbon block method incorporated into the PETRORISK model. The predicted BCFs for hydrocarbons are generally overly conservative since biotransformation is not quantitatively taken into account. Therefore, indirect exposure and resulting risk estimates predicted by PETRORISK are likely to be overestimated. For the purposes of PBT assessment, measured bioaccumulation data for representative hydrocarbon constituents have been used as detailed in section 8 of the CSR.
The QSAR used to calculated the BCF of icosane followed the Reach guidance indications (R7.10.3.2) and so is deemed suitable for the assessment of icosane bioconcentration.
The calculated BCF of icosane is 22 L/kg. This value indicates that icosane is not to be considered as a bioaccumulable substance.
Key value for chemical safety assessment
- BCF (aquatic species):
- 22 L/kg ww
Additional information
C14-20 Aliphatics (≤2% aromatic) are hydrocarbon UVCBs. Standard tests for this endpoint are intended for single substances and are not appropriate for these complex substances. However, this endpoint has been calculated for representative hydrocarbon structures using the BCFWIN v2.16 model within EPISuite 3.12 as input to the hydrocarbon block method incorporated into the PETRORISK model. The predicted BCFs for hydrocarbons are generally overly conservative since biotransformation is not quantitatively taken into account. Therefore, indirect exposure and resulting risk estimates predicted by PETRORISK are likely to be overestimated. For the purposes of PBT assessment, measured bioaccumulation data for representative hydrocarbon constituents have been used as detailed in section 8 of the CSR.
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