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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1988
Report date:
1988

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.2 (Acute Toxicity for Daphnia)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Propionaldehyde
EC Number:
204-623-0
EC Name:
Propionaldehyde
Cas Number:
123-38-6
Molecular formula:
C3H6O
IUPAC Name:
propanal

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no
Details on test solutions:
• A stock solution (500 mg/L) was prepared and subsequently diluted to achieve the test concentrations

Test organisms

Test organisms (species):
Daphnia magna
Details on test organisms:
• Source: Institut National de Recherche Chimique Appliquee (France), breed at the testing facility since 1987
• Age at study initiation: 0-24h
• Control group: yes

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h

Test conditions

Hardness:
2.61 mmol/L
Test temperature:
292-294 K
pH:
ranged from 7.14 to 8.15 in all test vessels including the control
Nominal and measured concentrations:
Nominal concentrations in mg/L: 7.81, 15.6, 31.2, 62.5, 125, 250 and 500 mg/L
Details on test conditions:
• Exposure vessel type: test-tube with flattened bottom, volume 10 mL, four vessels per test concentration
• Dilution water source: filtered tap water
• Dilution water chemistry (hardness: 2.7 +/- 0.5 mmol/L; pH: 7.7-8.3, Ca/Mg ratio 4:1)
• Test design: four replicates per treatment, five individuals per replicate, seven concentrations
• Method of calculating mean measured concentrations: statistical method of Spearman-Kaerber

Results and discussion

Effect concentrationsopen allclose all
Duration:
48 h
Dose descriptor:
EC0
Effect conc.:
62.5 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
88.7 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: 75.55 - 104.07 mg/L
Duration:
48 h
Dose descriptor:
EC100
Effect conc.:
250 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility

Any other information on results incl. tables

Effect concentrations after 24 hours: 
EC50: 134.3 [95%: 115.31 - 156.41]; EC0: 62.5; EC100: 250

Applicant's summary and conclusion