Registration Dossier
Registration Dossier
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EC number: 211-471-9 | CAS number: 646-25-3
Endpoint summary
Administrative data
Description of key information
Because decamethylenediamine is a strong base (pH = 12) the substance is classified into Skin Corr. Category 1B (H314: Causes severe skin burns and eye damage) and Eye Damage 1 (H318: Causes serious eye damage) according to EC Regulation 1272/2008.
Assessment of decamethylenediamine concerning respiratory irritation is also not possible because no data are available for this toxicological endpoint.
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation / corrosion
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
Eye irritation
Link to relevant study records
- Endpoint:
- eye irritation
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
According to REACH Annex VIII 8.1.1. column 2 an in vivo skin irritation study does not need to be conducted if the substance is classified as corrosive to the skin.
Justification for selection of eye irritation endpoint:
According to REACH Annex VIII 8.2.1. column 2 an in vivo eye irritation study does not need to be conducted if the substance is classified as corrosive to the skin.
Justification for classification or non-classification
Based on the chemical structure (aliphatic diamine) and due to the fact that decamethylenediamine is a strong base (pH = 12) the substance is classified into Skin Corr. Category 1B (H314: Causes severe skin burns and eye damage) and Eye Damage 1 (H318: Causes serious eye damage) according to EC Regulation 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
