Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

There are studies available conducted with Chlorhexidine digluconate as test substance. In fact the stability properties of the CHD-Base were determined.

Hydrolysis of Chlorhexidine digluconate was tested according to OECD Guideline 311 and EEC-Guideline C.07. No significant hydrolysis was observed at all pH values.Under environmental conditions the hydrolysis half-life of Chlorhexidine base is more than 1 year.

Direct photolysis rate constants and half lives for near surface clear natural water during spring, summer, fall, and winter at latitude 50° N were estimated based on the laboratory data. The estimated half-lifes were between 8.6 d in summer and 69.1 d in winter. A reaction rate for natural water bodies was not determined. Under natural conditions photolysis occurs exclusively near the water surface. In deeper water layers photolysis is inhibited by dullness and light disperion. Therefore, the determined reaction rates cannot be adopted for environmental half-lifes.