Registration Dossier
Registration Dossier
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EC number: 200-238-7 | CAS number: 55-56-1
Endpoint summary
Administrative data
Description of key information
Additional information
There are studies available conducted with Chlorhexidine digluconate as test substance. In fact the stability properties of the CHD-Base were determined.
Hydrolysis of Chlorhexidine digluconate was tested according to OECD Guideline 311 and EEC-Guideline C.07. No significant hydrolysis was observed at all pH values.Under environmental conditions the hydrolysis half-life of Chlorhexidine base is more than 1 year.
Direct photolysis rate constants and half lives for near surface clear natural water during spring, summer, fall, and winter at latitude 50° N were estimated based on the laboratory data. The estimated half-lifes were between 8.6 d in summer and 69.1 d in winter. A reaction rate for natural water bodies was not determined. Under natural conditions photolysis occurs exclusively near the water surface. In deeper water layers photolysis is inhibited by dullness and light disperion. Therefore, the determined reaction rates cannot be adopted for environmental half-lifes.
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