Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

The available tests on Chlorhexidine biodegradability allow no clear conclusion about the rate of biodegradation. In a Closed-Bottle-Test no biodegradation was observed.

However, it has been demonstrated that some bacterial strains can grow in a medium containing Chlorhexidine. Several intermediates were identified as degradation metabolites. As most of the available studies used isolated bacteria strains and the tests were run under laboratory conditions, the results do not allow a classification of biodegradability or a conclusion about degradation rates in biological treatment plants and in environmental compartments. Furthermore, it remains unresolved if those metabolites of chlorhexidine biodegradation that are observed in laboratory tests are also formed in relevant amounts under more realistic STP conditions. However, no evidence exist that biodegradation under laboratory conditions will rely on different pathways than under STP conditions.