Registration Dossier
Registration Dossier
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EC number: 700-352-1 | CAS number: 62756-44-9
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: recent test according to validated method
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: ECVAM (Final draft performance standards ATLA 35, 559-619, 2007
- GLP compliance:
- yes
Test material
- Reference substance name:
- (pyridin-3-yl)methanol hydrofluoride
- EC Number:
- 700-352-1
- Cas Number:
- 62756-44-9
- Molecular formula:
- C6H8FNO
- IUPAC Name:
- (pyridin-3-yl)methanol hydrofluoride
- Details on test material:
- Human epidermis model
Constituent 1
Test animals
- Species:
- human
Test system
- Type of coverage:
- open
- Preparation of test site:
- other: human epidermis model
- Vehicle:
- unchanged (no vehicle)
- Controls:
- yes
- Duration of treatment / exposure:
- 15min
- Observation period:
- 42h
- Number of animals:
- 3
Results and discussion
In vitro
Results
- Irritation / corrosion parameter:
- other: other: viability percentage
- Value:
- 100
- Remarks on result:
- other:
- Remarks:
- Basis: mean 100. Remarks: no mortality. (migrated information)
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: OECD GHS
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